(R)-1-Benzyloxycarbonylnipecotic acid - Names and Identifiers
Name | (R)-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester
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Synonyms | D-1-CBZ-NIPECOTIC ACID D-1-Cbz-Nipecotic Acid (R)-1-Benzyloxycarbonylnipecotic acid (R)-1-CBZ-PIPERIDINE-3-CARBOXYLIC ACID (R)-1-CBZ-PIPERIDINE-1-CARBOXYLIC ACID 1-Cbz-(3R)-3-piperidinecarboxylic acid (R)-1-Cbz-Piperidine-3-Carboxylic Acid 3(R)-N-(Carbobenzyloxy)-3-carboxypiperidine (R)-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester (R)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER (R)-1-[(BENZYLOXY)CARBONYL]PIPERIDINE-3-CARBOXYLIC ACID (3R)-1-[(Benzyloxy)Carbonyl]Piperidine-3-Carboxylic Acid
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CAS | 160706-62-7
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InChI | InChI=1/C14H17NO4/c16-13(17)12-7-4-8-15(9-12)14(18)19-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2,(H,16,17)/t12-/m1/s1 |
(R)-1-Benzyloxycarbonylnipecotic acid - Physico-chemical Properties
Molecular Formula | C14H17NO4
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Molar Mass | 263.29 |
Density | 1.265 |
Boling Point | 443.9±45.0 °C(Predicted) |
Flash Point | 222.3°C |
Vapor Presure | 1.16E-08mmHg at 25°C |
pKa | 4.48±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.568 |
(R)-1-Benzyloxycarbonylnipecotic acid - Introduction
(R)-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester is an organic compound. Its molecular formula is C12H11NO4 and its molecular weight is 237.22g/mol. The following is a description of its nature, use, formulation and safety information:
Nature:
- (R)-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester is a white crystalline solid or powder that can be dissolved in ketones, alcohols and non-polar organic solvents.
-Its melting point is 110-113 degrees Celsius.
-It has a certain chirality and is an optical isomer.
Use:
- (R)-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester is commonly used as an intermediate in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
-As a synthetic intermediate of chiral inducers such as chiral biphenyl, it is widely used in the pharmaceutical industry and pesticide industry.
Method:
- (R)-Piperidine-1, the preparation method of 3-Dicarboxylic Acid 1-Benzyl Ester is relatively complicated, and generally requires synthetic chemists to synthesize it through chemical synthesis. Common preparation methods include Chiral synthesis and reaction to obtain asymmetric products, which are then separated and purified by high performance liquid chromatography.
Safety Information:
- (R)-Piperidine-1, the specific harmfulness of 3-Dicarboxylic Acid 1-Benzyl Ester needs further research and evaluation.
-Use in accordance with relevant laboratory practices and wear personal protective equipment such as gloves and glasses.
-It should be stored in a dry, cool, well-ventilated place, and away from fire and oxidizing agents.
-Please read the relevant safety information and operating instructions carefully when using and storing, and follow proper handling and waste management practices.
Last Update:2024-04-09 02:00:42